s6 ribosomal protein (Cell Signaling Technology Inc)
Structured Review

S6 Ribosomal Protein, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 4737 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/stat1+protein/Stat1+Antibody/pmc12882742-179-8-11
Average 97 stars, based on 4737 article reviews
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1) Product Images from "Rapamycin Reverses the Hepatic Response to Diet‐Induced Metabolic Stress That Is Amplified by Aging"
Article Title: Rapamycin Reverses the Hepatic Response to Diet‐Induced Metabolic Stress That Is Amplified by Aging
Journal: Aging Cell
doi: 10.1111/acel.70395
Figure Legend Snippet: Rapamycin co‐treatment mitigates proinflammatory transcriptional hyperactivation in aged mice exposed to HFD. (A) Protocol: Mice received ND or eRapamycin‐containing diet from 4 to 18 months, followed by 9 weeks on HFD or ND. (B) Western blot of liver tissue. (C) Fold change of p‐S6/S6 compared to control diet. (D) PCA of RNA‐seq from isolated hepatocytes. (E) Number of DEGs across treatment groups. (F) Scatter plot comparing HFD‐induced gene expression changes (HFD + veh vs. ND + veh) to all gene expression changes with eRapamycin (eRapa+HFD vs. HFD + veh). (G) Heatmap of genes upregulated by HFD + vehicle treatment. (H) Venn diagram showing overlap between transcripts elevated by HFD versus ND and those decreased by rapamycin. (I) KEGG enrichment analysis of overlapping genes. (J) Heatmap of innate immune response genes. (K) Top transcription factor pathways predicted by IPA in the overlapping gene set. (L) Heatmap of Stat1 target genes. (M) Tumorigenic index score calculated per mouse. Statistical analyses for p‐S6/S6 ratios and tumorigenic index scores were performed using one‐way ANOVA with post hoc Tukey's test; p < 0.05 (*), p < 0.1 (**).
Techniques Used: Western Blot, Control, RNA Sequencing, Isolation, Gene Expression
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Article Title: Role of MSC-derived Galectin 3 in the AML Microenvironment Article Snippet: STAT1 , Article Title: Antagonism between viral infection and innate immunity at the single-cell level Article Snippet: STAT1 was reported to promote Article Title: The good and the bad faces of STAT1 in solid tumours. Article Snippet: Lee, STAT1 as a key modulator of Article Title: Interferon activates promoter of Nmi gene via interferon regulator factor-1. Article Snippet: N-Myc interactor (Nmi) is reported to participate in many activities, such as signaling transduction, transcription regulation, and antiviral responses.. As Nmi may play important roles in interferon (IFN)-induced responses, we investigated the mechanism how Nmi protein is regulated.. We identified and cloned the promoter of Nmi gene. Enzyme-linked Immunosorbent Assay:Article Title: IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis Article Snippet: Article Title: Chandipura virus induces cell death in cancer cell lines of human origin and promotes tumor regression in vivo Article Snippet: The phosphorylation status of STAT1 in cancer cells was assessed by treating the cells with 1,000 U of IFN-b for 24 h. The cell lysate collected from IFN-b-challenged and control-media-treated cells were subjected to immunoblotting to assess the levels of Article Title: Phosphatase wild-type p53-induced phosphatase 1 controls the development of T H 9 cells and allergic airway inflammation. Article Snippet: Phospho-STAT6 (Tyr641), STAT6, phospho-Smad3 319 (Ser423/425), Smad3, phospho-p38 MAPK (Thr180/Tyr182), P38, p-STAT5 320 (Tyr694), STAT5, p-STAT1 (Ser727), STAT1, phospho-SAPK/JNK 321 (Thr183/Tyr185), SAPK/JNK, phospho-c-Jun (Ser73), c-Jun, Rel-B, NF-κB p65, 322 β-Actin and Article Title: Estrogen promotes megakaryocyte polyploidization via estrogen receptor beta-mediated transcription of GATA1. Article Snippet: This is a PDF file of an unedited peer-reviewed manuscript that has been accepted for publication.. NPG are providing this early version of the manuscript as a service to our customers.. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Article Title: Role of MSC-derived Galectin 3 in the AML Microenvironment Article Snippet: STAT1 , Article Title: Antagonism between viral infection and innate immunity at the single-cell level Article Snippet: STAT1 was reported to promote Article Title: The good and the bad faces of STAT1 in solid tumours. Article Snippet: Lee, STAT1 as a key modulator of Article Title: Interferon activates promoter of Nmi gene via interferon regulator factor-1. Article Snippet: N-Myc interactor (Nmi) is reported to participate in many activities, such as signaling transduction, transcription regulation, and antiviral responses.. As Nmi may play important roles in interferon (IFN)-induced responses, we investigated the mechanism how Nmi protein is regulated.. We identified and cloned the promoter of Nmi gene. Knock-Out:Article Title: IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis Article Snippet: Article Title: Chandipura virus induces cell death in cancer cell lines of human origin and promotes tumor regression in vivo Article Snippet: The phosphorylation status of STAT1 in cancer cells was assessed by treating the cells with 1,000 U of IFN-b for 24 h. The cell lysate collected from IFN-b-challenged and control-media-treated cells were subjected to immunoblotting to assess the levels of Article Title: Phosphatase wild-type p53-induced phosphatase 1 controls the development of T H 9 cells and allergic airway inflammation. Article Snippet: Phospho-STAT6 (Tyr641), STAT6, phospho-Smad3 319 (Ser423/425), Smad3, phospho-p38 MAPK (Thr180/Tyr182), P38, p-STAT5 320 (Tyr694), STAT5, p-STAT1 (Ser727), STAT1, phospho-SAPK/JNK 321 (Thr183/Tyr185), SAPK/JNK, phospho-c-Jun (Ser73), c-Jun, Rel-B, NF-κB p65, 322 β-Actin and Article Title: Estrogen promotes megakaryocyte polyploidization via estrogen receptor beta-mediated transcription of GATA1. Article Snippet: This is a PDF file of an unedited peer-reviewed manuscript that has been accepted for publication.. NPG are providing this early version of the manuscript as a service to our customers.. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Article Title: Role of MSC-derived Galectin 3 in the AML Microenvironment Article Snippet: STAT1 , Article Title: Antagonism between viral infection and innate immunity at the single-cell level Article Snippet: STAT1 was reported to promote Article Title: The good and the bad faces of STAT1 in solid tumours. Article Snippet: Lee, STAT1 as a key modulator of Article Title: Interferon activates promoter of Nmi gene via interferon regulator factor-1. Article Snippet: N-Myc interactor (Nmi) is reported to participate in many activities, such as signaling transduction, transcription regulation, and antiviral responses.. As Nmi may play important roles in interferon (IFN)-induced responses, we investigated the mechanism how Nmi protein is regulated.. We identified and cloned the promoter of Nmi gene. Software:Article Title: IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis Article Snippet: Article Title: Chandipura virus induces cell death in cancer cell lines of human origin and promotes tumor regression in vivo Article Snippet: The phosphorylation status of STAT1 in cancer cells was assessed by treating the cells with 1,000 U of IFN-b for 24 h. The cell lysate collected from IFN-b-challenged and control-media-treated cells were subjected to immunoblotting to assess the levels of Article Title: Phosphatase wild-type p53-induced phosphatase 1 controls the development of T H 9 cells and allergic airway inflammation. Article Snippet: Phospho-STAT6 (Tyr641), STAT6, phospho-Smad3 319 (Ser423/425), Smad3, phospho-p38 MAPK (Thr180/Tyr182), P38, p-STAT5 320 (Tyr694), STAT5, p-STAT1 (Ser727), STAT1, phospho-SAPK/JNK 321 (Thr183/Tyr185), SAPK/JNK, phospho-c-Jun (Ser73), c-Jun, Rel-B, NF-κB p65, 322 β-Actin and Article Title: Estrogen promotes megakaryocyte polyploidization via estrogen receptor beta-mediated transcription of GATA1. Article Snippet: This is a PDF file of an unedited peer-reviewed manuscript that has been accepted for publication.. NPG are providing this early version of the manuscript as a service to our customers.. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Article Title: Role of MSC-derived Galectin 3 in the AML Microenvironment Article Snippet: STAT1 , Article Title: Antagonism between viral infection and innate immunity at the single-cell level Article Snippet: STAT1 was reported to promote Article Title: The good and the bad faces of STAT1 in solid tumours. Article Snippet: Lee, STAT1 as a key modulator of Article Title: Interferon activates promoter of Nmi gene via interferon regulator factor-1. Article Snippet: N-Myc interactor (Nmi) is reported to participate in many activities, such as signaling transduction, transcription regulation, and antiviral responses.. As Nmi may play important roles in interferon (IFN)-induced responses, we investigated the mechanism how Nmi protein is regulated.. We identified and cloned the promoter of Nmi gene. Phospho-proteomics:Article Title: IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis Article Snippet: Article Title: Chandipura virus induces cell death in cancer cell lines of human origin and promotes tumor regression in vivo Article Snippet: The phosphorylation status of STAT1 in cancer cells was assessed by treating the cells with 1,000 U of IFN-b for 24 h. The cell lysate collected from IFN-b-challenged and control-media-treated cells were subjected to immunoblotting to assess the levels of Article Title: Phosphatase wild-type p53-induced phosphatase 1 controls the development of T H 9 cells and allergic airway inflammation. Article Snippet: Phospho-STAT6 (Tyr641), STAT6, phospho-Smad3 319 (Ser423/425), Smad3, phospho-p38 MAPK (Thr180/Tyr182), P38, p-STAT5 320 (Tyr694), STAT5, p-STAT1 (Ser727), STAT1, phospho-SAPK/JNK 321 (Thr183/Tyr185), SAPK/JNK, phospho-c-Jun (Ser73), c-Jun, Rel-B, NF-κB p65, 322 β-Actin and Article Title: Estrogen promotes megakaryocyte polyploidization via estrogen receptor beta-mediated transcription of GATA1. Article Snippet: This is a PDF file of an unedited peer-reviewed manuscript that has been accepted for publication.. NPG are providing this early version of the manuscript as a service to our customers.. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Article Title: Role of MSC-derived Galectin 3 in the AML Microenvironment Article Snippet: STAT1 , Article Title: Antagonism between viral infection and innate immunity at the single-cell level Article Snippet: STAT1 was reported to promote Article Title: The good and the bad faces of STAT1 in solid tumours. Article Snippet: Lee, STAT1 as a key modulator of Article Title: Interferon activates promoter of Nmi gene via interferon regulator factor-1. Article Snippet: N-Myc interactor (Nmi) is reported to participate in many activities, such as signaling transduction, transcription regulation, and antiviral responses.. As Nmi may play important roles in interferon (IFN)-induced responses, we investigated the mechanism how Nmi protein is regulated.. We identified and cloned the promoter of Nmi gene. Control:Article Title: IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis Article Snippet: Article Title: Chandipura virus induces cell death in cancer cell lines of human origin and promotes tumor regression in vivo Article Snippet: The phosphorylation status of STAT1 in cancer cells was assessed by treating the cells with 1,000 U of IFN-b for 24 h. The cell lysate collected from IFN-b-challenged and control-media-treated cells were subjected to immunoblotting to assess the levels of Article Title: Phosphatase wild-type p53-induced phosphatase 1 controls the development of T H 9 cells and allergic airway inflammation. Article Snippet: Phospho-STAT6 (Tyr641), STAT6, phospho-Smad3 319 (Ser423/425), Smad3, phospho-p38 MAPK (Thr180/Tyr182), P38, p-STAT5 320 (Tyr694), STAT5, p-STAT1 (Ser727), STAT1, phospho-SAPK/JNK 321 (Thr183/Tyr185), SAPK/JNK, phospho-c-Jun (Ser73), c-Jun, Rel-B, NF-κB p65, 322 β-Actin and Article Title: Estrogen promotes megakaryocyte polyploidization via estrogen receptor beta-mediated transcription of GATA1. Article Snippet: This is a PDF file of an unedited peer-reviewed manuscript that has been accepted for publication.. NPG are providing this early version of the manuscript as a service to our customers.. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Article Title: Role of MSC-derived Galectin 3 in the AML Microenvironment Article Snippet: STAT1 , Article Title: Antagonism between viral infection and innate immunity at the single-cell level Article Snippet: STAT1 was reported to promote Article Title: The good and the bad faces of STAT1 in solid tumours. Article Snippet: Lee, STAT1 as a key modulator of Article Title: Interferon activates promoter of Nmi gene via interferon regulator factor-1. Article Snippet: N-Myc interactor (Nmi) is reported to participate in many activities, such as signaling transduction, transcription regulation, and antiviral responses.. As Nmi may play important roles in interferon (IFN)-induced responses, we investigated the mechanism how Nmi protein is regulated.. We identified and cloned the promoter of Nmi gene. Transduction:Article Title: IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis Article Snippet: Article Title: Chandipura virus induces cell death in cancer cell lines of human origin and promotes tumor regression in vivo Article Snippet: The phosphorylation status of STAT1 in cancer cells was assessed by treating the cells with 1,000 U of IFN-b for 24 h. The cell lysate collected from IFN-b-challenged and control-media-treated cells were subjected to immunoblotting to assess the levels of Article Title: Phosphatase wild-type p53-induced phosphatase 1 controls the development of T H 9 cells and allergic airway inflammation. Article Snippet: Phospho-STAT6 (Tyr641), STAT6, phospho-Smad3 319 (Ser423/425), Smad3, phospho-p38 MAPK (Thr180/Tyr182), P38, p-STAT5 320 (Tyr694), STAT5, p-STAT1 (Ser727), STAT1, phospho-SAPK/JNK 321 (Thr183/Tyr185), SAPK/JNK, phospho-c-Jun (Ser73), c-Jun, Rel-B, NF-κB p65, 322 β-Actin and Article Title: Estrogen promotes megakaryocyte polyploidization via estrogen receptor beta-mediated transcription of GATA1. Article Snippet: This is a PDF file of an unedited peer-reviewed manuscript that has been accepted for publication.. NPG are providing this early version of the manuscript as a service to our customers.. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Article Title: Role of MSC-derived Galectin 3 in the AML Microenvironment Article Snippet: STAT1 , Article Title: Antagonism between viral infection and innate immunity at the single-cell level Article Snippet: STAT1 was reported to promote Article Title: The good and the bad faces of STAT1 in solid tumours. Article Snippet: Lee, STAT1 as a key modulator of Article Title: Interferon activates promoter of Nmi gene via interferon regulator factor-1. Article Snippet: N-Myc interactor (Nmi) is reported to participate in many activities, such as signaling transduction, transcription regulation, and antiviral responses.. As Nmi may play important roles in interferon (IFN)-induced responses, we investigated the mechanism how Nmi protein is regulated.. We identified and cloned the promoter of Nmi gene. shRNA:Article Title: IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis Article Snippet: Article Title: Chandipura virus induces cell death in cancer cell lines of human origin and promotes tumor regression in vivo Article Snippet: The phosphorylation status of STAT1 in cancer cells was assessed by treating the cells with 1,000 U of IFN-b for 24 h. The cell lysate collected from IFN-b-challenged and control-media-treated cells were subjected to immunoblotting to assess the levels of Article Title: Phosphatase wild-type p53-induced phosphatase 1 controls the development of T H 9 cells and allergic airway inflammation. Article Snippet: Phospho-STAT6 (Tyr641), STAT6, phospho-Smad3 319 (Ser423/425), Smad3, phospho-p38 MAPK (Thr180/Tyr182), P38, p-STAT5 320 (Tyr694), STAT5, p-STAT1 (Ser727), STAT1, phospho-SAPK/JNK 321 (Thr183/Tyr185), SAPK/JNK, phospho-c-Jun (Ser73), c-Jun, Rel-B, NF-κB p65, 322 β-Actin and Article Title: Estrogen promotes megakaryocyte polyploidization via estrogen receptor beta-mediated transcription of GATA1. Article Snippet: This is a PDF file of an unedited peer-reviewed manuscript that has been accepted for publication.. NPG are providing this early version of the manuscript as a service to our customers.. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Article Title: Role of MSC-derived Galectin 3 in the AML Microenvironment Article Snippet: STAT1 , Article Title: Antagonism between viral infection and innate immunity at the single-cell level Article Snippet: STAT1 was reported to promote Article Title: The good and the bad faces of STAT1 in solid tumours. Article Snippet: Lee, STAT1 as a key modulator of Article Title: Interferon activates promoter of Nmi gene via interferon regulator factor-1. Article Snippet: N-Myc interactor (Nmi) is reported to participate in many activities, such as signaling transduction, transcription regulation, and antiviral responses.. As Nmi may play important roles in interferon (IFN)-induced responses, we investigated the mechanism how Nmi protein is regulated.. We identified and cloned the promoter of Nmi gene. Sequencing:Article Title: IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis Article Snippet: Article Title: Chandipura virus induces cell death in cancer cell lines of human origin and promotes tumor regression in vivo Article Snippet: The phosphorylation status of STAT1 in cancer cells was assessed by treating the cells with 1,000 U of IFN-b for 24 h. The cell lysate collected from IFN-b-challenged and control-media-treated cells were subjected to immunoblotting to assess the levels of Article Title: Phosphatase wild-type p53-induced phosphatase 1 controls the development of T H 9 cells and allergic airway inflammation. Article Snippet: Phospho-STAT6 (Tyr641), STAT6, phospho-Smad3 319 (Ser423/425), Smad3, phospho-p38 MAPK (Thr180/Tyr182), P38, p-STAT5 320 (Tyr694), STAT5, p-STAT1 (Ser727), STAT1, phospho-SAPK/JNK 321 (Thr183/Tyr185), SAPK/JNK, phospho-c-Jun (Ser73), c-Jun, Rel-B, NF-κB p65, 322 β-Actin and Article Title: Estrogen promotes megakaryocyte polyploidization via estrogen receptor beta-mediated transcription of GATA1. Article Snippet: This is a PDF file of an unedited peer-reviewed manuscript that has been accepted for publication.. NPG are providing this early version of the manuscript as a service to our customers.. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Article Title: Role of MSC-derived Galectin 3 in the AML Microenvironment Article Snippet: STAT1 , Article Title: Antagonism between viral infection and innate immunity at the single-cell level Article Snippet: STAT1 was reported to promote Article Title: The good and the bad faces of STAT1 in solid tumours. Article Snippet: Lee, STAT1 as a key modulator of Article Title: Interferon activates promoter of Nmi gene via interferon regulator factor-1. Article Snippet: N-Myc interactor (Nmi) is reported to participate in many activities, such as signaling transduction, transcription regulation, and antiviral responses.. As Nmi may play important roles in interferon (IFN)-induced responses, we investigated the mechanism how Nmi protein is regulated.. We identified and cloned the promoter of Nmi gene. Clone Assay:Article Title: IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis Article Snippet: Article Title: Chandipura virus induces cell death in cancer cell lines of human origin and promotes tumor regression in vivo Article Snippet: The phosphorylation status of STAT1 in cancer cells was assessed by treating the cells with 1,000 U of IFN-b for 24 h. The cell lysate collected from IFN-b-challenged and control-media-treated cells were subjected to immunoblotting to assess the levels of Article Title: Phosphatase wild-type p53-induced phosphatase 1 controls the development of T H 9 cells and allergic airway inflammation. Article Snippet: Phospho-STAT6 (Tyr641), STAT6, phospho-Smad3 319 (Ser423/425), Smad3, phospho-p38 MAPK (Thr180/Tyr182), P38, p-STAT5 320 (Tyr694), STAT5, p-STAT1 (Ser727), STAT1, phospho-SAPK/JNK 321 (Thr183/Tyr185), SAPK/JNK, phospho-c-Jun (Ser73), c-Jun, Rel-B, NF-κB p65, 322 β-Actin and Article Title: Estrogen promotes megakaryocyte polyploidization via estrogen receptor beta-mediated transcription of GATA1. Article Snippet: This is a PDF file of an unedited peer-reviewed manuscript that has been accepted for publication.. NPG are providing this early version of the manuscript as a service to our customers.. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Article Title: Role of MSC-derived Galectin 3 in the AML Microenvironment Article Snippet: STAT1 , Article Title: Antagonism between viral infection and innate immunity at the single-cell level Article Snippet: STAT1 was reported to promote Article Title: The good and the bad faces of STAT1 in solid tumours. Article Snippet: Lee, STAT1 as a key modulator of Article Title: Interferon activates promoter of Nmi gene via interferon regulator factor-1. Article Snippet: N-Myc interactor (Nmi) is reported to participate in many activities, such as signaling transduction, transcription regulation, and antiviral responses.. As Nmi may play important roles in interferon (IFN)-induced responses, we investigated the mechanism how Nmi protein is regulated.. We identified and cloned the promoter of Nmi gene. Plasmid Preparation:Article Title: IL-30 protects against sepsis-induced myocardial dysfunction by inhibiting pro-inflammatory macrophage polarization and pyroptosis Article Snippet: Article Title: Chandipura virus induces cell death in cancer cell lines of human origin and promotes tumor regression in vivo Article Snippet: The phosphorylation status of STAT1 in cancer cells was assessed by treating the cells with 1,000 U of IFN-b for 24 h. The cell lysate collected from IFN-b-challenged and control-media-treated cells were subjected to immunoblotting to assess the levels of Article Title: Phosphatase wild-type p53-induced phosphatase 1 controls the development of T H 9 cells and allergic airway inflammation. Article Snippet: Phospho-STAT6 (Tyr641), STAT6, phospho-Smad3 319 (Ser423/425), Smad3, phospho-p38 MAPK (Thr180/Tyr182), P38, p-STAT5 320 (Tyr694), STAT5, p-STAT1 (Ser727), STAT1, phospho-SAPK/JNK 321 (Thr183/Tyr185), SAPK/JNK, phospho-c-Jun (Ser73), c-Jun, Rel-B, NF-κB p65, 322 β-Actin and Article Title: Estrogen promotes megakaryocyte polyploidization via estrogen receptor beta-mediated transcription of GATA1. Article Snippet: This is a PDF file of an unedited peer-reviewed manuscript that has been accepted for publication.. NPG are providing this early version of the manuscript as a service to our customers.. The manuscript will undergo copyediting, typesetting and a proof review before it is published in its final form. Article Title: Role of MSC-derived Galectin 3 in the AML Microenvironment Article Snippet: STAT1 , Article Title: Antagonism between viral infection and innate immunity at the single-cell level Article Snippet: STAT1 was reported to promote Article Title: The good and the bad faces of STAT1 in solid tumours. Article Snippet: Lee, STAT1 as a key modulator of Article Title: Interferon activates promoter of Nmi gene via interferon regulator factor-1. Article Snippet: N-Myc interactor (Nmi) is reported to participate in many activities, such as signaling transduction, transcription regulation, and antiviral responses.. As Nmi may play important roles in interferon (IFN)-induced responses, we investigated the mechanism how Nmi protein is regulated.. We identified and cloned the promoter of Nmi gene. |
